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At a conference about ideas, it’s important to step back and consider the engine that creates them: the human mind. How exactly does the brain -- a three-pound snarl of electrochemically frantic nervous tissue -- create inspired inventions, the feeling of hunger, the experience of beauty, or the sense of self -- and how reliable is it? Dan Dennett contemplates the mind as an ecosystem in which a new class of entities -- memes -- can compete, coexist, reproduce and flourish, and asks what sorts of nefarious things these entities might be up to. An enthusiastic Dan Gilbert presents his new research on the peculiar, counterintuitive -- and perhaps a smidge deflating -- secret to happiness. And Jeff Hawkins explains why a napkin-sized sheaf of cellular matter, wrinkled into a ball, will fundamentally change the direction of the computer industry.