Insidermedicine Daily News (Video)
Insidermedicine is a daily health and medical video news service created by a leading physicians. Our content library contains videos in many languages including English, Chinese, Spanish, on over 100 different diseases. Joining the likes of the Associated Press and Reuters, Insidermedicine's newstories are featured ...
Insidermedicine is a daily health and medical video news service created by a leading physicians. Our content library contains videos in many languages including English, Chinese, Spanish, on over 100 different diseases. Joining the likes of the Associated Press and Reuters, Insidermedicine's newstories are featured by Google News and The News Room. April 25, 2007 Patients with HIV who are treated with protease inhibitors have an increased risk of heart attack, according to a study published in the New England Journal of Medicine. Combination antiretroviral therapy has had a dramatic effect in reducing illness and death associated with the HIV virus, however an earlier study showed that the risk of heart attacks increased by 17% with every year a patient spent on antiretroviral. It isn’t known, though, whether all antiretroviral drugs carry this risk. The assessment of the role of any specific drug is difficult because patients with HIV usually receive a combination of drugs, and often switch regimens because of the availability of newer substances, adverse events, or drug regimen failure. Previous studies have shown a relationship between the use of protease inhibitors, a class of antiretroviral drug, and cardiovascular disease, but there is little information on the risks associated with another class of antiretroviral therapy called nonnucleoside reverse-transcriptase inhibitors. In this study, more than 23,000 patients infected with the HIV virus were assessed to determine the incidence of heart attack and the association between heart attack and exposure to protease inhibitors or nonnucleoside reverse-transcriptase inhibitors. Confirming the earlier results, the researchers found the risk of having a heart attack increased by 16% per year of exposure to protease inhibitors alone, which is equal to twice the risk over five years. Not such effect was observed with nonnucleoside reverse-transcriptase inhibitors. It is thought that protease inhibitors raise the level of blood lipid, thereby increasing the risk of cardiovascular disease and heart attack. Patients treated with protease inhibitors should have their cholesterol and blood pressure levels monitored, and take steps to reduce their lifestyle-related risk factors. This includes maintaining a healthy weight, eating a low-fat diet rich in fruits in vegetables, and getting regular exercise. Reporting for Insidermedicine, I'm Dr. Susan Sharma.
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Breast Cancer Vaccine Shrinks Tumors in Mice; Factors for Stillbirth; HPV Blood Test Best for Detecting Cervical Cancer (Week in Review)
(December 17, 2011 - Insidermedicine) From Georgia - Scientists may ...
(December 17, 2011 - Insidermedicine) From Georgia - Scientists may be closer to developing a breast cancer vaccine, according to a report published in Proceedings of the National Academy of Sciences. Researchers developed a synthetic vaccine that was able activate the immune response in a mouse model, significantly shrinking both breast and pancreatic tumours that were 90% similar to human tumors. From Utah - Several factors may raise risk of stillbirth, according to a report published in JAMA. Researchers studied nearly 2500 deliveries in the US that took place over 2 years. They found that non-Hispanic black race, diabetes, age over 40, AB blood type, a history of drug addiction, smoking 3 months prior to pregnancy, obesity and not living with a partner all independently raised risk of stillbirth. And finally, from Bethesda - An HPV blood test is the best way to screen for cervical cancer in women over the age 30, according to a report published in the Lancet Oncology. Studying nearly 45,000 women for 5 years, researchers found that HPV testing found significantly more precancerous lesions than cytology, without resulting in over-diagnosis.
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HIV Treatment More Effective if Immediately Administered; Preventing Preterm Birth Possible with Progesterone; Exercise Declines Greatly Once Youth Attend College, University (Video)
(December 16, 2011 - Insidermedicine) From Milwaukee - Research published ...
(December 16, 2011 - Insidermedicine) From Milwaukee - Research published in the Journal of Infectious Diseases finds that immediate antiretroviral therapy is the best approach to treating early HIV infections. Researchers randomized 130 patients with early HIV to immediate antiretroviral therapy or until treatment was medically indicated. They found that the infection progressed much faster in those whose treatment was deferred. From Kentucky - Vaginal progesterone may help prevent preterm births, according to a report published in the American Journal of Obstetrics and Gynecology. Studying women with a short cervix--a known risk factor for premature delivery--researchers found that vaginal progesterone significantly reduced rates of births prior to 33 weeks gestation. And finally, from Hamilton - A new report published in the American Journal of Preventive Medicine finds that young adults frequently stop exercising once they attend university or college. Researchers followed over 600 adolescents until they were 24-27 years old, finding a 24% decrease in physical activity over the 12 year study period--with the decline greatest among men entering post secondary schooling.
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Dentists Could Screen Many Americans for Chronic Health Problems; Some Kidney Proteins Raise Risk of Premature Death; HPV Test Best for Cervical Cancer Detection (Video)
(December 15, 2011 - Insidermedicine) From New York - Dentists ...
(December 15, 2011 - Insidermedicine) From New York - Dentists could potentially screen nearly 20 million Americans for chronic health problems, according to a report published in the American Journal of Public Health. Researchers found that a significant portion of US adults and children routinely visit a dentist but not a health care provider. The authors suggest that dentists, as trained health care professionals, could potentially screen for diabetes and high blood pressure during the course of a normal visit. From Massachusetts - Elevated levels of certain kidney proteins may predict premature death, according to a report published in the Journal of the American Society of Nephrology. Researchers followed over 800 kidney disease patients for over 16 years, finding that higher levels of cystatic C and beta trace protein increased risk of dying prematurely. And finally, from Bethesda - HPV testing is the best way to screen for cervical cancer in women over the age 30, according to a report published in the Lancet Oncology. Studying nearly 45,000 women for 5 years, researchers found that HPV testing found significantly more precancerous lesions than cytology, without resulting in over-diagnosis.
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HIV Video: Scientists Discover Protein that Enhances HIV's Ability to Infect; Statins May Protect Flu Patients; Childhood Cancer Survivors Do Not Have Birth Defect Risk
(December 14, 2011 - Insidermedicine) From California - Scientists have ...
(December 14, 2011 - Insidermedicine) From California - Scientists have discovered proteins in the semen that enhances HIV's ability to infect new cells, according to a report published in Cell Host & Microbe. Examining 7 semen samples, researchers found that removing a set of fibrils from the semen severely diminished HIV's ability to attach to CD4 T white blood cells (immune cells that are HIV's primary target). From Portland - Statins may reduce death rates among patients hospitalized with the flu, according to a report published in the Journal of Infectious Diseases. Researchers studied over 3,000 patients hospitalized with the flu, finding that those who did not receive statins prior to, or during, hospitalization had a 2x increased risk of death. And finally, from Maryland - A new report published in the Journal of Clinical Oncology finds that childhood cancer survivors are not at increased risk of having a child with a birth defect. Researchers followed nearly 2800 childhood cancer survivors, finding no noticeable difference in birth defect rates among women who were treated with chemotherapy and radiation and those who did not receive either treatment. ...
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Stillbirth Risk Raises With Several Maternal Factors; Pathway Regulating Stress Discovered; Large DNA Study Identifies Genes Linked to Chronic Lymphocytic Leukemia (Video)
(December 13, 2011 - Insidermedicine) From Utah - Several factors ...
(December 13, 2011 - Insidermedicine) From Utah - Several factors may raise risk of stillbirth, according to a report published in JAMA. Researchers studied nearly 2500 deliveries in the US that took place over 2 years. They found that non-Hispanic black race, diabetes, age over 40, AB blood type, a history of drug addiction, smoking 3 months prior to pregnancy, obesity and not living with a partner all independently raised risk of stillbirth. From Massachusetts - Research published in the Journal of Neuroscience identifies a novel pathway that determines the body's response to stress. Researchers found that neurosteroids control the body's stress response. They able to block this response in a mouse model, effectively preventing stress-induced anxiety in the rodents. And finally, from Boston - A massive DNA study has found several gene abnormalities implicated in chronic lymphocytic leukaemia (CLL), according to a report published in the New England Journal of Medicine. Results of comprehensive DNA sequencing revealed five genetic mutations that were commonly associated with the blood cancer, an aspect which may improve predictions on progression of the disease.
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Scientists Make Breast Cancer Vaccine Progress; Chemotherapy Alone Improves Blood Cancer Survival; Ready-to-Bake Cookie Dough Linked to E. Coli (Video)
(December 12, 2011 - Insidermedicine) From Georgia - Scientists may ...
(December 12, 2011 - Insidermedicine) From Georgia - Scientists may be closer to developing a breast cancer vaccine, according to a report published in Proceedings of the National Academy of Sciences. Researchers developed a synthetic vaccine that was able activate the immune response in a mouse model, significantly shrinking both breast and pancreatic tumours that were 90% similar to human tumors. From Kingston - Research published in the New England Journal of Medicine finds that chemotherapy alone may improve survival in some blood cancer patients. Randomizing patients with Hodgkin's lymphoma to either chemotherapy alone, radiation plus chemotherapy, or radiation alone, researchers found that those treated with only chemotherapy were more likely to be alive a year after treatment started. And finally, Atlanta - Ready-to-bake cookie dough has been linked to E. coli, according to a report published in Clinical Infectious Diseases. CDC researchers examined a multi-state E. Coli outbreak in 2009, finding nearly 80 patients who developed illnesses from ready to eat cookie dough, resulting in 35 hospitalizations.
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Cardiotoxicity of cancer treatments; Lasting impact of child abuse, neglect; Fish with Omega-3 for heart disease risk (Week in review)
(December 11, 2011, Insidermedicine) From Euroecho, the annual meeting of ...
(December 11, 2011, Insidermedicine) From Euroecho, the annual meeting of the European Association of Echocardiography, researchers are working toward developing protocols for evaluating myocardial damage associated with different cancer treatments. As treatments for cancer have improved survival rates in patients, the long-term effects of these treatments are of growing concern. Cardiotoxicity is a common side-effect of many cancer treatments, and the current research projects aim to identify when patients might benefit from changes in cancer therapy, and when protective treatments against cardiotoxicity are indicated. From New Haven, researchers at the Yale School of Medicine have found that adolescents exposed to neglect or abuse (either physical or emotional) earlier in life show lastings signs in the form of a reduction in grey matter in their brains. Grey matter is the tissue within the brain that contains brain cells. The researchers noted gender differences in the grey matter deficits: boys tended to lose impulse control and be more prone to substance abuse, while girls showed a tendency toward depression. From Denmark, young women who eat fish containing omega 3 fatty acids are at reduced risk for heart disease. Looking at women of childbearing age, the researchers from the Technical University of Denmark found that women who never ate fish were at a 90% increased risk of cardiovascular disease as compared to women who ate fish high in omega-3 on a weekly basis.
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Breast Cancer Videos: Starch intake & risk; obesity, diabetes & risk; Effective diets for prevention (Week in review)
From the San Antonio Breast Cancer Symposium, starch intake has ...
From the San Antonio Breast Cancer Symposium, starch intake has been linked to an increased risk of breast cancer recurrence, according to research out of the University of California, San Diego. The researchers followed breast cancer survivors and tracked their dietary starch intake. The results showed that in women with lower-grade tumours, increased starch intake coincided with a 46% increase in risk for breast cancer recurrence. Also from the San Antonio Breast Cancer Symposium, researchers from Lund University in Sweden have revealed that women over the age of 60 who are diabetic and obese have a significantly higher risk for breast cancer. Obesity itself increased breast cancer risk by 55%, while diabetes increased risk by 37%. The researchers also noted breast cancer risk associated with different diabetes drugs, finding the metformin lowered risk by 8%, while glargine almost doubled the risk. And finally, intermittent low-carb diets appear to be more successful than daily calorie-restricted diets at reducing weight, and lowering blood levels of insulin, two factors known to be associated with risk for developing cancer. The researchers from the Genesis Prevention Center in Manchester compared a standard calorie-restricted daily Mediterranean diet to two, 2-day-a-week, low-carb diets: one calorie restricted, the other not. The researchers found that both of the intermittent diets were more successful than daily dieting at reducing weight, body fat, and insulin resistance.
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Extreme endurance athletes' heart health; Blood pressure medications in dialysis patients; Tuberculosis risk in postpartum mothers (video)
(December 9, 2011 - Insidermedicine) From Melbourne, athletes engaging extreme ...
(December 9, 2011 - Insidermedicine) From Melbourne, athletes engaging extreme endurance exercise may incur damage to the right ventricles of their hearts. While most of the athletes studied showed an apparent reversal of any damage, athletes who had been training and competing in endurance sports for a longer time showed signs of permanent damage in the form of scarring of the heart muscle. This research points to the need for a better understanding of the right ventricle's susceptibility to exercise-induced heart injury. This research should not be misinterpreted as an argument against the health benefits of exercise. From Washington, two apparently similar classes of medicines for treating high blood pressure have very different impacts on the heart health of dialysis patients. Heart disease is a leading cause of death in dialysis patients. The researchers found that ACE inhibitors were better at preventing blood vessel damage, while Angiotensin Receptor Blockers (ARBs) were better at preventing inflammation. This research highlights the need to better understand the different effects of blood pressure-lowering medications on dialysis patients, and to adopt a personalized approach to therapy. And finally, from the UK, postpartum mothers are at increased risk for tuberculosis in the six months following pregnancy, according to research from the Health Protection Agency and the University of East Anglia. Tuberculosis is an infectious disease that is most effectively managed though early treatment. The current research supports targeted TB screening of pregnant and postpartum women.
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Starch intake linked to breast cancer recurrence; BP lowering medications reduce stroke risk in certain patients; Intermittent low-carb most effective for reducing weight (Video)
(December 8, 2011 - Insidermedicine) From the San Antonio Breast ...
(December 8, 2011 - Insidermedicine) From the San Antonio Breast Cancer Symposium, starch intake has been linked to an increased risk of breast cancer recurrence, according to research out of the University of California, San Diego. The researchers followed breast cancer survivors and tracked their dietary starch intake. The results showed that in women with lower-grade tumours, increased starch intake coincided with a 46% increase in risk for breast cancer recurrence. From Cleveland, blood pressure medicines prescribed to patients with prehypertension have the effect of lowering the risk of stroke. Researchers from the Harrington-McLaughlin Heart and Vascular Institute found that blood pressure-lowering medicines accounted for a 22% lower risk of stroke in prehypertensive patients, though the risk of heart attack had no significant change. The researchers were quick to point out that lifestyle changes, rather than medications, are the gold standard for addressing prehypertension. And finally, also from the San Antonio Breast Cancer Symposium, intermittent low-carb diets appear to be more successful than daily calorie-restricted diets at reducing weight, and lowering blood levels of insulin, two factors known to be associated with risk for developing cancer. The researchers from the Genesis Prevention Center in Manchester compared a standard calorie-restricted daily Mediterranean diet to two, 2-day-a-week, low-carb diets: one calorie restricted, the other not. The researchers found that both of the intermittent diets were more successful than daily dieting at reducing weight, body fat, and insulin resistance.
